Browsing by Subject "Dictyostelium discoideum"
Now showing items 1-13 of 13
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(1977)The temporal development of Dictyostelium discoideum is altered by the disruption of pyrimidine metabolism in amoeba during mitotic cell division or following nutritional starvation. The well-defined differentiation process ...
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(2020-06-04)Very little is known about how tissues can regulate their size. In one possible mechanism, cells in a tissue secrete a factor that inhibits their proliferation, and as the tissue gets bigger, the concentration of the factor ...
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(2014-10-14)Cancer is a group of diseases characterized by uncontrolled cell proliferation. Cancer is responsible for nearly 1 of every 4 deaths, and ranks as the second highest cause of death worldwide, and costs the American population ...
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(Texas A&M University. Libraries, 1984)Pyrimidine nucleotides may be provided for cellular growth via a de novo biosynthetic pathway or salvage pathways of interconversion of nucleosides and bases. The de novo biosynthesis in D. discoideum is provided by the ...
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(1982)The research reported in this thesis demonstrates that the initial steps for pyrimidine biosynthesis in the cellular slime mold Dictyostelium discoideum are catalyzed by the enzymes carbamoyl phosphate synthetase (CPSase, ...
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(1978)The cellular slime mold Dictyostelium discoideum is a good organism for studying the excision repair process. The fungicide benomyl is known to have some unusual mutagenic properties; for this reason, we studied its effects ...
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(1977)A key point in the regulation of pyrimidine biosynthesis by prokaryotic organisms is the enzyme Aspartate Transcarbamylase. This enzyme catalyzes the reaction of carbamyl phosphate plus aspartate to yield carbamyl aspartate, ...
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Phosphorus is an atom taken up by cells as inorganic phosphate (Pi). The mechanism behind how cells measure cellular Pi levels is not well understood. SPX domains are positively charged helical bundles located at the ...
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Polyphosphate acts as a chalone in single celled Dictyostelium discoideum, accumulation of the extracellular signal in the external environment causes cells to halt proliferation and proceed to the next stage of their life ...
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(2020-04-23)Polyphosphate is a molecule ubiquitous throughout all domains of life that has a wide variety of physiological roles. It is especially prevalent in bacteria, where it modulates stress responses, survival, quorum sensing ...
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The goal of this project is to determine how physiological levels of polyphosphate affect cellular metabolism in the model organism Dictyostelium discoideum. Understanding the effects of polyphosphate on a molecular level ...
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(1979)The studies reported in this paper examine the metabolic reorientation of purine nucleotide metabolism during the development of the cellular slime mold, Dictyostelium discoideum. There appears to be an energy oriented ...
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(1978)In these studies, Dictyostelium discoideum nucleotide metabolism during cellular development was examined. Aspartate Transcarbamylase (ATCase) is the first enzyme unique to pyrimidine synthesis de novo and it was found to ...